Slc7a13 Gene Summary [Rat]

Predicted to enable L-amino acid transmembrane transporter activity and protein heterodimerization activity. Predicted to be involved in L-cystine transport; L-glutamate transmembrane transport; and aspartate transmembrane transport. Predicted to be active in apical plasma membrane. Orthologous to human SLC7A13 (solute carrier family 7 member 13). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Slc7a13
Official Name
solute carrier family 7 member 13 [Source:RGD Symbol;Acc:1311633]
Ensembl ID
ENSRNOG00000024903
Bio databases IDs NCBI: 313089 Ensembl: ENSRNOG00000024903
Aliases solute carrier family 7 member 13
Synonyms 0610009O04Rik, AGT-1, solute carrier family 7, (cationic amino acid transporter, y+ system) member 13, solute carrier family 7 member 13, XAT2
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc7a13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • amino acid permease
  • L-type amino acid transporter
  • protein binding
  • protein heterodimerization
  • transporter

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • renal clear cell adenocarcinoma
  • renal clear cell cancer
regulated by
regulates
  • L-glutamic acid
  • L-aspartic acid
  • L-cystine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane
  • apical membrane
  • basolateral membrane
  • brush border membrane vesicles

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Slc7a13 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • L-glutamate transport
  • L-cystine transport
  • amino acid transmembrane transport
  • aspartate transport

Cellular Component

Where in the cell the gene product is active
  • apical plasma membrane

Molecular Function

What the gene product does at the molecular level
  • L-amino acid transmembrane transporter activity
  • antiporter activity
  • protein heterodimerization activity

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.