SLC7A13 Gene Summary [Human]
Predicted to enable L-amino acid transmembrane transporter activity. Predicted to be involved in L-cystine transport; L-glutamate transmembrane transport; and aspartate transmembrane transport. Predicted to be integral component of membrane. Predicted to be active in apical plasma membrane. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | SLC7A13 |
| Official Name | solute carrier family 7 member 13 [Source:HGNC Symbol;Acc:HGNC:23092] |
| Ensembl ID | ENSG00000164893 |
| Bio databases IDs | |
| Aliases | solute carrier family 7 member 13 |
| Synonyms | 0610009O04Rik, AGT-1, solute carrier family 7, (cationic amino acid transporter, y+ system) member 13, solute carrier family 7 member 13, XAT2 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human SLC7A13 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- amino acid permease
- L-type amino acid transporter
- protein binding
- protein heterodimerization
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- apical membrane
- basolateral membrane
- brush border membrane vesicles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human SLC7A13 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- L-glutamate transport
- L-cystine transport
- amino acid transmembrane transport
- aspartate transport
Cellular Component
Where in the cell the gene product is active
- apical plasma membrane
Molecular Function
What the gene product does at the molecular level
- L-amino acid transmembrane transporter activity
- antiporter activity
- protein heterodimerization activity