Kiz Gene Summary [Rat]
Predicted to enable protein kinase binding activity. Predicted to be involved in spindle organization. Predicted to be located in cytoplasm. Predicted to be active in centrosome. Human ortholog(s) of this gene implicated in retinitis pigmentosa 69. Orthologous to human KIZ (kizuna centrosomal protein). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kiz |
| Official Name | kizuna centrosomal protein [Source:RGD Symbol;Acc:1307071] |
| Ensembl ID | ENSRNOG00000025141 |
| Bio databases IDs | |
| Aliases | kizuna centrosomal protein |
| Synonyms | C20orf19, Gm114, HT013, Kizuna, kizuna centrosomal protein, NCRNA00153, PLK1S1, RGD1307071, RP69 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kiz often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein kinase binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- pervasive developmental disorder
- attention deficit hyperactivity disorder
- retinitis pigmentosa type 69
- retinitis pigmentosa
- retinal dystrophy
- lupus nephritis
- KIZ-related retinopathy
- peanut allergy
role in cell
- misalignment
- organization
- misalignment in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- centrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Kiz gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- spindle organization
Cellular Component
Where in the cell the gene product is active
- centrosome
- cytoplasm
- cell projection
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- protein binding