Capn11 Gene Summary [Rat]

Predicted to enable calcium-dependent cysteine-type endopeptidase activity. Predicted to be involved in proteolysis. Predicted to be located in acrosomal vesicle. Predicted to be active in cytoplasm. Orthologous to human CAPN11 (calpain 11). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Capn11
Official Name
calpain 11 [Source:RGD Symbol;Acc:1302946]
Ensembl ID
ENSRNOG00000026025
Bio databases IDs NCBI: 408218 Ensembl: ENSRNOG00000026025
Aliases calpain 11
Synonyms calpain 11, protease
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Capn11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • The penta-EF hand (PEF) family
  • Calpain family cysteine protease
  • calpain
  • EF hand
  • peptidase
  • EFh
  • Calpain_III
  • CysPc

Pathways

Biological processes and signaling networks where the Capn11 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • congenital heart disease
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • acrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Capn11 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • cytoplasm
  • acrosomal vesicle

Molecular Function

What the gene product does at the molecular level
  • calcium ion binding
  • peptidase activity
  • calcium-dependent cysteine-type endopeptidase activity

Gene-Specific Assays for Results You Can Trust

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