Prss53 Gene Summary [Rat]

Predicted to enable serine-type endopeptidase activity. Predicted to be involved in proteolysis. Orthologous to human PRSS53 (serine protease 53). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Prss53
Official Name
serine protease 53 [Source:RGD Symbol;Acc:1566127]
Ensembl ID
ENSRNOG00000026040
Bio databases IDs NCBI: 499270 Ensembl: ENSRNOG00000026040
Aliases serine protease 53
Synonyms mFLJ00289, POL3S, RGD1311277, RGD1566127, serine protease 53, UNQ308
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Prss53 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Trypsin-like serine protease
  • trypsin
  • Tryp_SPc
  • Domain of unknown function (DUF1986)
  • protein binding

Pathways

Biological processes and signaling networks where the Prss53 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • androgenic alopecia
  • dermatophytosis
  • onychomycosis
regulated by
  • AGT
  • alitretinoin
  • L-triiodothyronine

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Unknown

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Prss53 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • proteolysis

Cellular Component

Where in the cell the gene product is active
  • extracellular region

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • serine-type endopeptidase activity