Slc10a4 Gene Summary [Rat]
Predicted to enable bile acid:sodium symporter activity. Predicted to be involved in bile acid and bile salt transport and regulation of neurotransmitter loading into synaptic vesicle. Predicted to act upstream of or within adult behavior and response to xenobiotic stimulus. Predicted to be located in plasma membrane. Predicted to be active in several cellular components, including dopaminergic synapse; serotonergic synapse; and synaptic vesicle membrane. Orthologous to human SLC10A4 (solute carrier family 10 member 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Slc10a4 |
| Official Name | solute carrier family 10, member 4 [Source:RGD Symbol;Acc:1309536] |
| Ensembl ID | ENSRNOG00000026091 |
| Bio databases IDs | |
| Aliases | solute carrier family 10, member 4 |
| Synonyms | E130304D01, P4, solute carrier family 10 member 4, solute carrier family 10, member 4, solute carrier family 10 (sodium/bile acid cotransporter family), member 4 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slc10a4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- bile acid transporter
- protein binding
- Sodium Bile acid symporter family
- Predicted Na+-dependent transporter YfeH [General function prediction only]
- transporter
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- synaptic vesicle membrane
- intracellular compartment
- intracellular space
- synapse
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Slc10a4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sodium ion transport
- transmembrane transport
- bile acid and bile salt transport
Cellular Component
Where in the cell the gene product is active
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- bile acid:sodium symporter activity
- protein binding