Tmem218 Gene Summary [Rat]

Predicted to be located in cilium. Predicted to be integral component of membrane. Implicated in Joubert syndrome. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Protein Coding
Official Symbol
Tmem218
Official Name
transmembrane protein 218 [Source:RGD Symbol;Acc:1311364]
Ensembl ID
ENSRNOG00000008757
Bio databases IDs NCBI: 300516 Ensembl: ENSRNOG00000008757
Aliases transmembrane protein 218
Synonyms 1810021J13Rik, CR626017, JBTS39, LOC219854, RGD1311364, transmembrane protein 218
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tmem218 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • lung adenocarcinoma
  • lung adenocarcinoma formation
  • Joubert syndrome type 39
  • Joubert syndrome type 1
  • Meckel syndrome type 4
regulated by
  • testosterone

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Extracellular Space

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Tmem218 gene, providing context for its role in the cell.

Cellular Component

Where in the cell the gene product is active
  • membrane
  • cilium

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.