Tekt3 Gene Summary [Rat]
Predicted to be involved in cilium assembly and flagellated sperm motility. Predicted to act upstream of with a positive effect on regulation of brood size. Located in acrosomal membrane and sperm flagellum. Human ortholog(s) of this gene implicated in spermatogenic failure 81. Orthologous to human TEKT3 (tektin 3). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Tekt3 |
| Official Name | tektin 3 [Source:RGD Symbol;Acc:1310582] |
| Ensembl ID | ENSRNOG00000027212 |
| Bio databases IDs | |
| Aliases | tektin 3 |
| Synonyms | 4933407G07RIK, SPGF81, tektin 3 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Tekt3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- protein binding
- Tektin family
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- axonemes
- sperm tail
- acrosome
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Tekt3 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- sperm motility
- cilium morphogenesis
- cilium movement involved in cell motility
- regulation of brood size
Cellular Component
Where in the cell the gene product is active
- nucleus
- axonemal microtubule
- microtubule cytoskeleton
- extracellular vesicular exosome
- acrosomal membrane
- outer acrosomal membrane
- acrosomal vesicle
- sperm flagellum
Molecular Function
What the gene product does at the molecular level
- protein binding