TEKT3 Gene Summary [Human]

This gene product belongs to the tektin family of proteins. Tektins comprise a family of filament-forming proteins that are coassembled with tubulins to form ciliary and flagellar microtubules. The exact function of this gene is not known. [provided by RefSeq, Jul 2008]

Details

Type
Processed Transcript
Official Symbol
TEKT3
Official Name
tektin 3 [Source:HGNC Symbol;Acc:HGNC:14293]
Ensembl ID
ENSG00000125409
Bio databases IDs NCBI: 64518 Ensembl: ENSG00000125409
Aliases tektin 3
Synonyms 4933407G07RIK, SPGF81, tektin 3
Species
Human, Homo sapiens
OrthologiesMouseRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human TEKT3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • protein binding
  • Tektin family

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • asthenozoospermia
  • spermatogenic failure 81
  • hairpin sperm flagellum
role in cell
  • motility
  • assembly

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • axonemes
  • sperm tail
  • acrosome

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human TEKT3 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • sperm motility
  • cilium morphogenesis
  • cilium movement involved in cell motility
  • regulation of brood size

Cellular Component

Where in the cell the gene product is active
  • nucleus
  • axonemal microtubule
  • microtubule cytoskeleton
  • extracellular vesicular exosome
  • acrosomal membrane
  • outer acrosomal membrane
  • acrosomal vesicle
  • sperm flagellum

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

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