Cep68 Gene Summary [Rat]
Predicted to enable protein domain specific binding activity and protein kinase binding activity. Predicted to be involved in centriole-centriole cohesion and protein localization to organelle. Predicted to be located in several cellular components, including cytosol; microtubule organizing center; and nucleoplasm. Orthologous to human CEP68 (centrosomal protein 68). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cep68 |
| Official Name | centrosomal protein 68 [Source:RGD Symbol;Acc:1309101] |
| Ensembl ID | ENSRNOG00000027282 |
| Bio databases IDs | |
| Aliases | centrosomal protein 68 |
| Synonyms | 6030463E10Rik, AI481761, centrosomal protein 68, KIAA0582, RGD1309101 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cep68 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- SPEC
- Spectrin repeats
- protein kinase binding
- protein domain specific binding
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- essential hypertension
- hypertension
- major depression
- atrial fibrillation
- diabetes mellitus
- non-insulin-dependent diabetes mellitus
- diabetic retinopathy
- atrial flutter
- arrhythmia
- diabetic neuropathy
regulated by
- EKI-785
role in cell
- cycling
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cell junction
- basal bodies
- centrosome
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Cep68 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- centrosome cycle
- centriole-centriole cohesion
- protein localization to organelle
Cellular Component
Where in the cell the gene product is active
- centrosome
- centriolar satellite
- cell junction
- cytosol
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein kinase binding
- protein domain specific binding
- protein binding