Kb23 Gene Summary [Rat]
Predicted to be a structural constituent of skin epidermis. Predicted to be involved in hair cycle; intermediate filament organization; and keratinization. Predicted to be located in intermediate filament. Predicted to be active in keratin filament. Human ortholog(s) of this gene implicated in erythrokeratodermia variabilis et progressiva 5 and monilethrix. Orthologous to several human genes including KRT83 (keratin 83). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kb23 |
| Official Name | type II keratin 23 [Source:RGD Symbol;Acc:1303024] |
| Ensembl ID | ENSRNOG00000030814 |
| Bio databases IDs | |
| Aliases | type II keratin 23 |
| Synonyms | 5430421N21Rik, Kb23, keratin 83 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Kb23 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- TPR/MLP1/MLP2-like protein
- structural constituent of cytoskeleton
- Intermediate filament protein
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- intermediate filaments
- keratin intermediate filaments