Wdr46 Gene Summary [Rat]
Predicted to be involved in maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA). Predicted to be part of small-subunit processome. Predicted to be active in nucleolus. Orthologous to human WDR46 (WD repeat domain 46). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Wdr46 |
| Official Name | WD repeat domain 46 [Source:RGD Symbol;Acc:2209] |
| Ensembl ID | ENSRNOG00000031171 |
| Bio databases IDs | |
| Aliases | WD repeat domain 46 |
| Synonyms | 2310007I04Rik, BING4, C6orf11, FP221, UTP7, WD repeat domain 46 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Wdr46 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- BING4CT (NUC141) domain
- WD40 repeats
- WD domain, G-beta repeat
- enzyme
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- pre-ribosome
- nucleoplasm
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Wdr46 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)
- ribosomal small subunit biogenesis
Cellular Component
Where in the cell the gene product is active
- small-subunit processome
- nucleolus
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- RNA binding