Details
| Type | Protein Coding |
| Official Symbol | Slco1a2 |
| Official Name | solute carrier organic anion transporter family, member 1A2 [Source:RGD Symbol;Acc:70985] |
| Ensembl ID | ENSRNOG00000031249 |
| Bio databases IDs | |
| Aliases | solute carrier organic anion transporter family, member 1A2 |
| Synonyms | OATP-3, Slc21a7, Slco1a2, solute carrier organic anion transporter family, member 1A5 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Slco1a2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Organic Anion Transporter Polypeptide (OATP) family
- Major Facilitator Superfamily
- sodium-independent organic anion transporter
- monocarboxylic acid transporter
- bile acid transporter
- thyroid hormone transporter
- KAZAL_FS
- organic anion transporter
- transporter
Pathways
Biological processes and signaling networks where the Slco1a2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- proximal tubular toxicity
regulated by
- beta-estradiol
- growth hormone
regulates
- bile acid
- bile salt
- thyroid hormone
- taurocholic acid
- monocarboxylic acid
- organic anion
role in cell
- number
- abnormal morphology
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- cellular membrane
- apical cell surfaces
- apical membrane
- basal membrane
- brush border