Eif1a Gene Summary [Rat]
Enables ribosomal large subunit binding activity. Predicted to be involved in translational initiation. Predicted to be active in cytoplasm. Orthologous to human EIF1AX (eukaryotic translation initiation factor 1A X-linked) and EIF1AY (eukaryotic translation initiation factor 1A Y-linked). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Eif1a |
| Official Name | eukaryotic translation initiation factor 1A [Source:RGD Symbol;Acc:1306331] |
| Ensembl ID | ENSRNOG00000031421 |
| Bio databases IDs | |
| Aliases | eukaryotic translation initiation factor 1A |
| Synonyms | Ef1a, Eftu, eIF-4C, eukaryotic translation initiation factor 1A |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Eif1a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- S1_like
- Translation initiation factor 1A / IF-1
- ribosomal large subunit binding
Pathways
Biological processes and signaling networks where the Eif1a gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- myelin enriched fraction
- Cytoplasm
- Mitochondria