Details

Type
Protein Coding
Official Symbol
Cyp2b3
Official Name
cytochrome P450, family 2, subfamily b, polypeptide 3 [Source:RGD Symbol;Acc:628627]
Ensembl ID
ENSRNOG00000033164
Bio databases IDs NCBI: 286953 Ensembl: ENSRNOG00000033164
Aliases cytochrome P450, family 2, subfamily b, polypeptide 3
Synonyms Cyp2b, Cyp2b13, Cyp2b3, Cyp2b6, Cyp2b9, CYPIIB3, cytochrome P450, family 2, subfamily b, polypeptide 13, cytochrome P450, family 2, subfamily b, polypeptide 3, cytochrome P450, family 2, subfamily b, polypeptide 9, LOC100359973, P-450pb-b, RGD:619923
Species
Rat, Rattus norvegicus
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Cyp2b3 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • cytochrome P450 (CYP) superfamily
  • Cytochrome P450
  • testosterone 16-alpha-hydroxylase
  • reduced flavin or flavoprotein:oxygen oxidoreductase
  • monooxygenase
  • enzyme
  • steroid hydroxylase
  • heme binding
  • NADH2 or NADPH2 1 atom incorporation:oxygen oxidoreductase

Pathways

Biological processes and signaling networks where the Cyp2b3 gene in rat plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • epithelial cancer
  • hepatocellular carcinoma
  • liver cancer
  • proximal tubular toxicity
regulated by
  • lipopolysaccharide
  • andrographolide
  • GADD45B
  • phenobarbital
  • methylprednisolone
  • clofibrate
  • HNF4A
  • STAT5A
  • berberine
  • RORC
regulates
  • 4-biphenylamine
  • 4,4'-methylenebis(2-chloroaniline)

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • endoplasmic reticulum membrane

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.