Zfp777 Gene Summary [Rat]
Predicted to enable DNA-binding transcription factor activity, RNA polymerase II-specific and RNA polymerase II transcription regulatory region sequence-specific DNA binding activity. Predicted to be involved in negative regulation of cell population proliferation; protein heterooligomerization; and regulation of DNA-templated transcription. Predicted to be active in nucleus. Orthologous to human ZNF777 (zinc finger protein 777). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zfp777 |
| Official Name | zinc finger protein 777 [Source:RGD Symbol;Acc:1566056] |
| Ensembl ID | ENSRNOG00000033639 |
| Bio databases IDs | |
| Aliases | zinc finger protein 777 |
| Synonyms | 2500002G23Rik, RGD1566056, Zfp777, zinc finger protein 777 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zfp777 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Zinc finger, C2H2 type
- krueppel associated box
- zinc finger
- C2H2-type zinc-finger domain
- Zinc-finger double domain
- protein binding
- KRAB (Kruppel-associated box) domain -A box
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Zfp777 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of transcription, DNA-dependent
- negative regulation of cell proliferation
- protein heterooligomerization
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- DNA binding
- sequence-specific DNA binding transcription factor activity
- protein binding
- metal ion binding