Raet1e Gene Summary [Rat]
Predicted to enable natural killer cell lectin-like receptor binding activity. Predicted to be involved in several processes, including antigen processing and presentation of endogenous peptide antigen via MHC class I via ER pathway, TAP-independent; antigen processing and presentation of endogenous peptide antigen via MHC class Ib; and positive regulation of T cell mediated cytotoxicity. Predicted to be active in external side of plasma membrane and extracellular space. Orthologous to human RAET1E (retinoic acid early transcript 1E). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Raet1e |
| Official Name | retinoic acid early transcript 1E [Source:RGD Symbol;Acc:1311118] |
| Ensembl ID | ENSRNOG00000040300 |
| Bio databases IDs | |
| Aliases | retinoic acid early transcript 1E |
| Synonyms | LOC102546867, RAE-1B6, RAE-1delta, Rae-1 epsilon, Rae-1 ε, Raet1c, Raet1d, Raet1e, Raet1l, Raet1ll1, Raet1ll2, retinoic acid early transcript 1E, retinoic acid early transcript 1L, retinoic acid early transcript 1L like 1, retinoic acid early transcript 1L like 2, retinoic acid early transcript delta, retinoic acid early transcript gamma, retinoic acid early transcript γ, retinoic acid early transcript δ, Rrlt, UL16 binding protein 1, Ulbp1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Raet1e often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Class I Histocompatibility antigen, domains alpha 1 and 2
- natural killer cell lectin-like receptor binding
- ectodomain
- receptor agonist activity
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- intracellular membrane-bounded organelle
- cell surface
- Extracellular Space
- cytosol
- plasma membrane extracellular face