RGD1559459 Gene Summary [Rat]
Predicted to enable glucuronosyltransferase activity. Predicted to be involved in steroid metabolic process. Predicted to be located in endoplasmic reticulum and nuclear outer membrane. Orthologous to human UGT2B28 (UDP glucuronosyltransferase family 2 member B28) and UGT2B4 (UDP glucuronosyltransferase family 2 member B4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | RGD1559459 |
| Official Name | similar to Expressed sequence AI788959 [Source:RGD Symbol;Acc:1559459] |
| Ensembl ID | ENSRNOG00000042714 |
| Bio databases IDs | |
| Aliases | similar to Expressed sequence AI788959 |
| Synonyms | LOC105377266, RGD1559459, UDP glucuronosyltransferase 2 family, polypeptide B34 like 1, UDP glucuronosyltransferase family 2 member B11, Ugt2b34l1 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rgd1559459 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- glycosyltransferase family 1 and related proteins with GTB topology
- glycosyltransferase, MGT family
- enzyme
- protein binding
- UDP-glucoronosyl and UDP-glucosyl transferase
- glucuronosyltransferase
Pathways
Biological processes and signaling networks where the Rgd1559459 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- microsome
- outer nuclear membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rgd1559459 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- xenobiotic glucuronidation
- estrogen metabolic process
- cellular glucuronidation
- xenobiotic metabolic process
Cellular Component
Where in the cell the gene product is active
- endoplasmic reticulum membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- glucuronosyltransferase activity