Rp1l1 Gene Summary [Rat]
Predicted to be involved in several processes, including axoneme assembly; photoreceptor cell development; and photoreceptor cell maintenance. Predicted to be located in photoreceptor connecting cilium and photoreceptor outer segment. Predicted to be active in axoneme. Human ortholog(s) of this gene implicated in occult macular dystrophy and retinitis pigmentosa 88. Orthologous to human RP1L1 (RP1 like 1). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Rp1l1 |
| Official Name | RP1 like 1 [Source:RGD Symbol;Acc:1586886] |
| Ensembl ID | ENSRNOG00000046326 |
| Bio databases IDs | |
| Aliases | RP1 like 1 |
| Synonyms | AC270276.1, BE983540, Dcdc4, DCDC4B, OCMD, retinitis pigmentosa 1 homolog like 1, RP1HL1, RP1 like 1, RP88 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Rp1l1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Doublecortin
- Ubl1_cv_Nsp3_N-like
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- retinitis pigmentosa type 88
- retinal dystrophy
- occult macular dystrophy
- neuroticism
- suicide
- abnormality of the integument
- autosomal recessive retinitis pigmentosa
- osteoarthritis
- retinitis pigmentosa
- optic atrophy
role in cell
- degeneration
- abnormal morphology
- development
- number
- maintenance
- electrophysiology
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- axonemes
- connecting cilia
- photoreceptor outer segments
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Rp1l1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- retina development in camera-type eye
- photoreceptor cell maintenance
- photoreceptor cell development
- axoneme assembly
- visual perception
- intracellular signal transduction
Cellular Component
Where in the cell the gene product is active
- photoreceptor connecting cilium
- axoneme
- photoreceptor outer segment
- microtubule