Klrc2 Gene Summary [Rat]
Predicted to enable MHC class I protein complex binding activity; activating MHC class Ib receptor activity; and protein antigen binding activity. Predicted to be involved in natural killer cell mediated immunity; positive regulation of natural killer cell degranulation; and stimulatory C-type lectin receptor signaling pathway. Predicted to be located in external side of plasma membrane. Predicted to be part of receptor complex. Orthologous to several human genes including KLRC2 (killer cell lectin like receptor C2). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Klrc2 |
| Official Name | killer cell lectin like receptor C2 [Source:RGD Symbol;Acc:2977] |
| Ensembl ID | ENSRNOG00000052467 |
| Bio databases IDs | |
| Aliases | killer cell lectin like receptor C2 |
| Synonyms | killer cell lectin like receptor C2, NKG2C, Nkg2E, rNKG2C |
| Species | Rat, Rattus norvegicus |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Klrc2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- signaling receptor activity
- binding protein
- C-type lectin (CTL)/C-type lectin-like (CTLD) domain
- Lectin C-type domain
- antigen binding
- protein binding
- transmembrane receptor
Pathways
Biological processes and signaling networks where the Klrc2 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- plasma membrane extracellular face