Zfp488 Gene Summary [Rat]
Predicted to enable zinc ion binding activity. Predicted to be involved in oligodendrocyte development; positive regulation of myelination; and regulation of DNA-templated transcription. Predicted to act upstream of or within negative regulation of DNA-templated transcription and positive regulation of oligodendrocyte differentiation. Predicted to be active in nucleus. Orthologous to human ZNF488 (zinc finger protein 488). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Zfp488 |
| Official Name | zinc finger protein 488 [Source:RGD Symbol;Acc:1309835] |
| Ensembl ID | ENSRNOG00000057542 |
| Bio databases IDs | |
| Aliases | zinc finger protein 488 |
| Synonyms | Gm1206, Zfp488, zinc finger protein 488 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Zfp488 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- zinc finger
- transcription regulator
- protein binding
- C2H2-type zinc finger
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Zfp488 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- oligodendrocyte development
- negative regulation of transcription, DNA-dependent
- regulation of transcription, DNA-dependent
- positive regulation of oligodendrocyte differentiation
- positive regulation of myelination
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- DNA binding
- protein binding
- metal ion binding