Oas1h Gene Summary [Rat]
Predicted to enable double-stranded RNA binding activity. Predicted to be involved in innate immune response; interleukin-27-mediated signaling pathway; and negative regulation of viral genome replication. Predicted to be active in cytosol; membrane; and nucleoplasm. [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Oas1h |
| Official Name | 2 ' -5 ' oligoadenylate synthetase 1H [Source:RGD Symbol;Acc:1359732] |
| Ensembl ID | ENSRNOG00000057769 |
| Bio databases IDs | |
| Aliases | 2 ' -5 ' oligoadenylate synthetase 1H |
| Synonyms | 2'-5' oligoadenylate synthetase 1D, 2'-5' oligoadenylate synthetase 1E, 2 ' -5 ' oligoadenylate synthetase 1H, LOC100910214, LOC103689988, Oas1c, Oas1d, Oas1e, Oasl6 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Oas1h often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- 2'-5'-oligoadenylate synthetase 1, domain 2, C-terminus
- Nucleotidyltransferase (NT) domain of DNA polymerase beta and similar proteins
- double-stranded RNA binding
- enzyme
- 2'-5'-oligoadenylate synthetase
Pathways
Biological processes and signaling networks where the Oas1h gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
- NFkB (complex)
- HRAS
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- ribosome
- Nucleus
- Mitochondria
- cytosol
- nucleoplasm