Target List
Covers specific hotspots of the targeted genes based on the Human GRCh38 genome build
Exons
NRASPDGFRAPIK3CAPMS2CL
Exons & Hotspots
PMS2
Hotspots
ABL1AKT1ALBALKAPOBARARAFARID1AARID2ATMAXIN1BRAFCCND1CCNE1CDH1CDKN2ACHEK2CREBBPCSF1RCSF3RCTNNB1DPYDERBB3ERCC1ERCC2ESR1EZH2FANCMFBXW7FGFR2FGFR3FLT3FOXA1FOXL2GNASHRASIDH1IDH2JAK1JAK2KDM6AKEAP1KMT2DMAP2K1MAPK1MED12MPLMSH6MYCMYD88NF2NFE2L2NOTCH1NTRK1PIK3R1POLEPPP2R1APTPN11RB1RETRIT1RNF43ROS1RRASRRAS2RUNX1SF3B1SMAD4SPOPSRSF2STAT3STK11TCF7L2TGFBR2TSC2U2AF1UGT1A1
Promoter
TERT
Promoter & Hotspots
APCMLH1MSH2PTEN
Whole Coding
BRCA1BRCA2EGFRERBB2KRASMETTP53
Bladder Cancers
AKT1ARID1AATMBRAFCCND1CCNE1CDKN2ACTNNB1ERBB2ERBB3ERCC2FGFR2FGFR3HRASJAK2KDM6AKRASMPLPIK3CAPTENRB1TP53U2AF1
Brain Cancers
ALKAPCBRAFBRCA2CDKN2ACHEK2CREBBPCTNNB1EGFRERBB2FGFR3IDH1IDH2KITKRASMETMLH1MSH2MYCNF2NOTCH1NRASPDGFRAPIK3CAPMS2PMS2CLPTENPTPN11RB1STK11TERTTP53
Breast Cancers
AKT1ARARAFATMBRCA1BRCA2CCND1CDH1CHEK2EGFRERBB2ERBB3ESR1FBXW7FGFR2FLT3JAK2KITKRASMETMLH1MPLMSH2MSH6MYCPDGFRAPIK3CAPMS2PMS2CLPPP2R1APTENRUNX1SF3B1STK11TP53U2AF1
Cervical Cancers
ARAFMAPK1MPL
Colorectal Cancers
AKT1APCARID1AATMBRAFBRCA1BRCA2CDKN2ACHEK2CSF1RCTNNB1DPYDEGFRERBB2ERBB3ERCC1ESR1FBXW7FGFR3FLT3GNASHRASJAK2KITKRASMAP2K1METMLH1MPLMSH2MSH6MYCNRASPDGFRAPIK3CAPMS2PMS2CLPOLEPTENRETRNF43SMAD4SRSF2STK11TCF7L2TGFBR2TP53UGT1A1
Gastric Cancers
APCARAFARID1ABRAFCDH1CDKN2ACTNNB1ERBB2ERBB3FBXW7GNASJAK2KITKMT2DKRASMETMPLMYCPDGFRAPIK3CAPTENRNF43SMAD4SRSF2TP53
Liver Cancers
ALBAPCAPOBARID1AARID2AXIN1BRAFCCND1CDKN2ACREBBPCTNNB1IDH1IDH2JAK1JAK2KEAP1KRASMYCNFE2L2NRASPIK3CARB1RIT1TP53TSC2
Lung Cancers
ABL1AKT1ALKARAFATMBRAFBRCA1BRCA2CCND1CDKN2ACHEK2CSF3RCTNNB1EGFRERBB2FGFR3FLT3HRASIDH1JAK2KITKRASMAP2K1METMLH1MPLMSH2MSH6MYCNF2NRASNTRK1PDGFRAPIK3CAPMS2PMS2CLPTENRB1RETROS1RRASSTK11TP53TSC2U2AF1
Lymphomas
ARID1AATMBRAFCCND1CDKN2ACHEK2CREBBPEZH2GNASIDH1IDH2JAK1KMT2DMAP2K1MYCMYD88NOTCH1NRASPIK3CASF3B1STAT3TP53
Melanomas
ARID2ATMBRAFBRCA1BRCA2CCND1CDKN2ACHEK2CREBBPCTNNB1EGFREZH2HRASIDH1KITKRASMAP2K1MLH1MSH2MSH6NRASPDGFRAPIK3CAPTENRB1TP53
Ovarian Cancers
AKT1ARID1AATMBRAFBRCA1BRCA2CCND1CCNE1CDH1CDKN2ACHEK2CTNNB1ERBB2ERBB3ERCC1FANCMFBXW7FGFR2FGFR3FOXL2KITKRASMLH1MPLMSH2MSH6MYCPDGFRAPIK3CAPIK3R1PMS2PMS2CLPOLEPPP2R1APTENRB1RRAS2STK11TP53
Pancreatic Cancers
APCARID1AATMBRAFBRCA1BRCA2CDKN2ACTNNB1ERBB2ERBB3FBXW7GNASJAK2KDM6AKRASMETMLH1MSH2MSH6MYCNRASPIK3CAPMS2PMS2CLPOLEPTENRNF43SMAD4STK11TCF7L2TP53U2AF1
Prostate Cancers
AKT1APCARARAFATMBRAFBRCA1BRCA2CHEK2CTNNB1FOXA1HRASIDH1JAK2KDM6AKMT2DKRASMED12MLH1MPLMSH2MSH6MYCPIK3CAPIK3R1PMS2PMS2CLPTENRB1SPOPTP53U2AF1