Target List
G1 Phase & G1/S Transition
Cdk6, Cdkn3, Gpr132, Itgb1, Nfatc1, Skp2, Slfn1 (QuantiNova Symbol: AC128859.3)
S Phase & DNA Replication
Cdc6, Cdc7, Mcm2, Mcm3, Mcm4, Mki67, Mre11a, Msh2, Rad17, Rad51
G2 Phase & G2/M Transition
Birc5, Cdkn3, Ppm1d (Wip1), Stt3a
M Phase
Aurkb, Brca2, Ccna1, Ccnb1, Cdc20, Cdc25a, Cdc25b, Cdc25c, Cdc6, Cdk1, Cdk2, Nek2, Rad21, Ran, Shc1, Smc1a, Stag1, Stmn1, Terf1, Wee1
Cell Cycle Checkpoint & Cell Cycle Arrest
Brca2, Casp3, Cdc25c, Cdk1, Cdk5rap1, Cdkn1a (Cip1, Waf1), Cdkn1b (P27KIP1), Cdkn2a (INK4A, p16, p19ARF), Cdkn2b (p15), Cdkn3, Chek2, Ddit3 (Gadd153, Chop), Dst, Gadd45a, Hus1, Inha, Mad2l1, Mdm2, Msh2, Nbn (Nbs1), Notch2, Pkd1, Pmp22, Ppm1d (Wip1), Rad9a (Rad9), Rb1, Sesn2, Sfn (14-3-3σ), Slfn1 (QuantiNova Symbol: AC128859.3), Smc1a, Stt3a, Tsg101
Regulation of the Cell Cycle
Aurka, Bcl2, Brca2, Ccna1, Ccna2, Ccnb1, Ccnb3, Ccnc, Ccnd1, Ccnd2, Ccnd3, Ccne1, Ccnf, Cdc20, Cdc25c, Cdc6, Cdk1, Cdk4, Cdk6, Cdkn1a (Cip1, Waf1), E2f1, E2f3, E2f4, Gadd45a, Itgb1, LOC100909750 (Abl1), Rad9a (Rad9), Ran, Rb1, Sfn (14-3-3σ), Shc1, Skp2, Tfdp2
Negative Regulation of the Cell Cycle
Atm, Brca1, Casp3, Cdkn2a (INK4A, p16, p19ARF), Inha, Rbl1, Rbl2, Tp53 (p53), Tp63