Target List
Regulation of Adipogenesis
Adipokines
Adig, Adipoq, Cfd, Lep (Leptin), Retn
Hormones
Agt, Angpt2
Lipases
Lipe, Lpl
PPARγ Targets
Adipoq, Agt, Cebpa, Cfd, Fabp4, Fasn, Irs2, Klf15, Lipe, Lpl, Pparg, Ppargc1a (Pgc-1alpha), Retn, Sirt3, Slc2a4 (Glut4), Srebf1
Adipogenesis Regulation
Pro-Adipogenesis
Acacb, Axin1, Ccnd1, Cdk4, Cebpb, Cebpd, Dkk1, E2f1, Fabp4, Fasn, Fgf1, Fgf2 (bFGF), Irs2, Jun, Lmna, Lpl, Pparg, Rxra, Sfrp1, Sfrp5, Slc2a4 (Glut4), Wnt5b
Anti-Adipogenesis
Adrb2, Cdkn1a (p21Cip1, Waf1), Cdkn1b (p27Kip1), Ddit3 (Gadd153, Chop), Dlk1, Foxo1, Hes1, Lrp5, Ncor2, Runx1t1, Shh, Sirt1, Sirt2, Taz, Tcf7l2, Tsc22d3, Vdr, Wnt1, Wnt3a
Pro-White Adipose Tissue
Bmp2, Bmp4, Cebpa, Egr2, Fgf10, Klf15, Klf4, Srebf1
Anti-White Adipose Tissue
Gata2, Gata3, Klf2, Klf3
Pro-Brown Adipose Tissue
Bmp7, Creb1, Dio2, Foxc2, Insr, Irs1, Mapk14 (p38alpha), Nrf1, Ppara, Ppard, Ppargc1a (Pgc-1alpha), Ppargc1b, Prdm16, Sirt3, Src, Ucp1, Wnt5a
Anti-Brown Adipose Tissue
Ncoa2, Nr0b2, Nr1h3, Rb1, Twist1, Wnt10b