Target List
Skeletal Development
Cartilage Condensation
Bmp1, Bmpr1b (Alk6), Col2a1, Sox9
Ossification
Acvr1 (Alk2), Ahsg (QuantiNova Symbol: AABR07034632.1), Bglap, Bmp1, Bmp2, Bmp3, Bmp4, Bmp5, Bmp6, Bmp7, Bmpr1a (Alk3), Bmpr1b (Alk6), Bmpr2, Cdh11, Chrd, Col1a1, Col2a1, Csf1 (Mcsf), Ctsk, Dlx5, Fgf2 (bFGF), Fgfr2, Gdf10 (Bmp3b), Gli1, Igf1, Igf1r, Ihh, LOC103689974 (Tnfsf11), Mmp2, Mmp8, Mmp9, Nog, Runx2, Smad1, Smad3, Sost, Sox9, Sp7, Spp1, Tgfb1, Tgfb2, Tgfb3, Twist1
Osteoclast Differentiation
Bglap, Csf1 (Mcsf), LOC103689974 (Tnfsf11), LOC103694380 (Tnf)
Osteoblast Differentiation
Acvr1 (Alk2), Bglap, Bmp2, Bmp4, Bmp6, Bmp7, Bmpr1a (Alk3), Bmpr1b (Alk6), Bmpr2, Chrd, Col1a1, Dlx5, Fgf2 (bFGF), Fgfr2, Gdf10 (Bmp3b), Gli1, Igf1, Ihh, Nog, Runx2, Smad1, Smad3, Sp7, Spp1, Twist1
Other Skeletal Development Genes
Alpl, Comp, Fgfr1, Tgfbr1 (Alk5), Tgfbr2, Tgfbr3
Bone Mineral Metabolism
Bone Mineralization
Acvr1 (Alk2), Ahsg (QuantiNova Symbol: AABR07034632.1), Bglap, Bmp2, Bmp4, Bmp6, Bmp7, Bmpr1a (Alk3), Bmpr1b (Alk6), Bmpr2, Fgfr2, Igf1, Smad3, Sox9, Tgfb1, Tgfb3, Twist1
Calcium Ion Binding & Homeostasis
Anxa5, Bglap, Cdh11, Comp, Egf, Fgf2 (bFGF), Itgav, Itgb1, Mmp2, Mmp8, Tgfb1, Vdr
Extracellular Matrix (ECM) Molecules
Collagens
Col10a1, Col14a1, Col1a1, Col1a2, Col2a1, Col3a1, Col4a1, Col5a1, Col6a1
Extracellular Matrix (ECM) Protease Inhibitors
Ahsg (QuantiNova Symbol: AABR07034632.1), Serpinh1 (Hsp47)
Extracellular Matrix (ECM) Proteases
Ctsk, Mmp10, Mmp2, Mmp8, Mmp9, Phex
Other Extracellular Matrix (ECM) Molecules
Alpl, Bgn, Flt1 (Vegfr1)
Cell Adhesion Molecules
Cell-Cell Adhesion
Bmp1, Bmpr1b (Alk6), Cdh11, Col14a1, Col2a1, Icam1, Ihh, Itgb1, LOC103689974 (Tnfsf11), LOC103694380 (Tnf), Sox9, Tgfb1, Vcam1
Cell-Extracellular Matrix (ECM) Adhesion
Cd36 (QuantiNova Symbol: RGD1565355), Col3a1, Csf1 (Mcsf), Itga2, Itga3, Itgad, Itgav, Itgb1, Smad3
Other Cell Adhesion Molecules
Bglap, Col5a1, Comp, Fn1, LOC103694380 (Tnf)
Growth Factors
Csf2 (Gm-csf), Csf2 (Gm-csf), Csf2 (Gm-csf), Csf3 (Gcsf), Egf, Fgf1, Fgf2 (bFGF), Gdf10 (Bmp3b), Igf1, Pdgfa, Vegfa, Vegfb
Transcription Factors
Gli1, Nfkb1, Runx2, Smad1, Smad2, Smad3, Smad4, Smad5, Sox9, Twist1