GeneGlobe ID: PAHS-030Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

RT² Profiler™ PCR Array Human Insulin Signaling Pathway

RT2 Profiler PCR Array
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Product Specification

Target List
Insulin Receptor-Associated Proteins
Insulin & Receptors​
INS, INSL3, IRS1, IRS2, IRS4, SORBS1
Insulin-Like Growth Factors & Receptors​
IGF1R, IGF2, IGFBP1
SH3 / SH2 Adaptor Proteins​
CBL, GAB1, GRB2, IRS4, NCK1
Other Insulin Receptor-Associated Proteins​
CAP1, DOK1, DOK2, DOK3, FRS2, FRS3, INSR, PDPK1, PPP1CA, PTPN1 (PTP1B), PTPRF, SHC1
PI3 Kinase Signaling
PI3 Kinase Canoncial Pathway Genes​
AKT1, AKT2, AKT3, EIF2B1, EIF4EBP1 (4E-BP1), GSK3A, GSK3B, MTOR, PDPK1, PIK3CA (p110-alpha), PIK3R1 (p85-ALPHA), PIK3R2 (p85-BETA), PRKCG, PRKCI, PRKCZ
PI3 Kinase Signaling Target Genes​
BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), DUSP14, G6PC, HK2, IGFBP1, PCK2, SERPINE1 (PAI-1), SLC2A4 (GLUT4), SREBF1, UCP1, VEGFA
MAP Kinase Signaling
MAP Kinase Canoncial Pathway Genes​
ARAF, BRAF, EIF2B1, GRB2, HRAS, MAP2K1, MAPK1 (ERK2), RAF1, RPS6KA1, RRAS, RRAS2, SHC1, SOS1
MAP Kinase Signaling Target Genes​
ANG, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), ERCC1, FOS, LDLR, NOS2 (iNOS), UCP1
Primary Insulin Signaling Target Genes
CEBPA, CEBPB, FOS, JUN, LEP (Leptin), PRL
Secondary Insulin Signaling Effector Target Genes
NPY, PCK2, SLC2A1, SLC2A4 (GLUT4), TG
PPARγ Targets
ACOX1, ADRB3, AEBP1, CAP1, CEBPA, CEBPB, PCK2, PPARG, RETN
SREBP1 Targets
ACACA, FBP1, G6PC, GCK, PCK2, PKM
Carbohydrate Metabolism
Glucose Metabolism​
FBP1, G6PC, GCK, HK2, INS, IRS2, PCK2, PKM, SLC2A1, SLC2A4 (GLUT4), SORBS1
Glycogen Metabolism​
G6PC, GSK3B, PPP1CA
Other Carbohydrate Metabolism Genes​
ADRB3, GPD1, INSR
Lipid Metabolism
Cholesterol Metabolism​
LDLR, SREBF1
Fatty Acid Metabolism​
ACACA, ACOX1, FASN
Lipid Transport​
LDLR, SORBS1
Other Lipid Metabolism Genes​
ARAF, BRAF, INS, LEP (Leptin), PPARG, PRKCG, PRKCI, PRKCZ, RAF1, SHC1
Protein Metabolism
Protein Phosphatases​
DUSP14, PPP1CA, PTPN1 (PTP1B), PTPRF
Protein Kinases​
AKT1, AKT2, AKT3, ARAF, BRAF, GSK3A, GSK3B, IGF1R, INSL3, INSR, MAP2K1, MAPK1 (ERK2), PDPK1, PRKCG, PRKCI, PRKCZ, RAF1, RPS6KA1
Protein Biosynthesis​
ANG, EIF2B1, EIF4EBP1 (4E-BP1), LDLR, PPP1CA
Protein Transport​
PRKCI, RRAS2
Other Protein Metabolism Genes​
AEBP1, CBL, DOK1, DOK2, FRS2, GAB1, IRS1, NOS2 (iNOS), SORBS1, VEGFA
Transcription Factors & Regulators
Transcriptional Regulation​
CEBPA, CEBPB, FOS, JUN, PPARG, SREBF1
Transcription Factors​
AEBP1, CBL, CEBPA, CEBPB, FOS, JUN, PPARG, SREBF1
Cell Growth & Differentiation
Cell Cycle​
HK2, HRAS, IGF1R, IGF2, KRAS, MAPK1 (ERK2), MTOR, VEGFA
Cell Proliferation​
GAB1, IGF1R, IGF2, IRS2, NCK1, NPY, PRL, RAF1, SHC1, VEGFA
Growth Factors & Receptors​
GAB1, GRB2, IGF1R, IGF2, IGFBP1, INSR, SHC1, VEGFA
Cell Differentiation​
NOS2 (iNOS), PPARG
Gene Resource List
Array Layout for PCR Plates
File Size: 138.31 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 132 KBLanguage: English

Resources

Brochures & Guides (3)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Download Files (3)
For analyzing gene expression data from RT2 Profiler PCR Arrays 
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

Scientific Posters (1)
Poster for download
Kit Handbooks (1)
For pathway-focused gene expression profiling using real-time RT-PCR
Instrument Technical Documents (2)
For gene expression and genomic analysis
For pathway-focused gene expression analysis
Certificates of Analysis (1)
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