GeneGlobe ID: PAHS-225Z | Cat. No.: 330231 | RT2 Profiler PCR Arrays

RT² Profiler™ PCR Array Human NFkB Signaling Targets

RT2 Profiler PCR Array
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Product Specification

Target List
Cytokines & Chemokines
CCL11 (Eotaxin), CCL2 (MCP-1), CCL22 (MDC), CCL5 (RANTES), CSF1 (MCSF), CSF2 (GM-CSF), CSF3 (GCSF), CXCL1 (GRO1, GROa, SCYB1), CXCL10 (INP10), CXCL2 (GRO2, GROb, SCYB2), CXCL9 (MIG), FASLG (TNFSF6), IFNB1, IFNG, IL12B, IL15, IL1A, IL1B, IL1RN, IL2, IL4, IL6, CXCL8 (IL8), LTA (TNFB), LTB, TNF, TNFSF10 (TRAIL)
Inflammation
Acute Inflammation​
C3, CCL5 (RANTES), CFB, F3, F8, IL1A, IL1B, IL6, INS, STAT3, STAT5B
Other Pro-Inflammatory Genes​
AGT, AKT1, CCL11 (Eotaxin), CCL2 (MCP-1), CCL22 (MDC), CCR5, CD40 (TNFRSF5), CXCL1 (GRO1, GROa, SCYB1), CXCL10 (INP10), CXCL2 (GRO2, GROb, SCYB2), CXCL9 (MIG), IL15, IL1RN, IL2, IL2RA (CD25), CXCL8 (IL8), MYD88, PTGS2 (COX2), SELE, SELP, TNF, TNFRSF1B
Apoptosis
AGT, BIRC2 (c-IAP1), EGFR (ERBB1), FASLG (TNFSF6), GADD45B, IFNB1, IFNG, IL12B, IL2RA (CD25), IL4, INS, LTA (TNFB), MAP2K6 (MEK6, MKK6), MMP9, NQO1, NR4A2 (NURR1), PTGS2 (COX2), STAT1, TNFRSF1B, TNFSF10 (TRAIL), TP53 (p53), TRAF2
Anti-Apoptotic
ADM, AKT1, BCL2A1 (BFL1), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BIRC3 (c-IAP2), CCL2 (MCP-1), CDKN1A (p21CIP1, WAF1), CSF2 (GM-CSF), F3, FAS, IL1A, IL1B, IL2, IL6, MYD88, NFKBIA (IκBα, MAD3), SOD2, STAT5B, TNF, XIAP
Immune Response
Innate Immunity​
C3, CCL2 (MCP-1), CFB, IFNB1, IL12B, IL6, INS, MYD88, NFKBIA (IκBα, MAD3), STAT5B, TNF
Adaptive Immunity​
C3, CCL2 (MCP-1), CD40 (TNFRSF5), CD80, ICAM1, IFNG, IL12B, IL1B, IL2, IL4, TRAF2
Other Immune Response Genes​
CD83, FAS, FASLG (TNFSF6), IL1R2, CXCL8 (IL8), LTA (TNFB), LTB, TNFSF10 (TRAIL)
Type I Interferon Responsive Genes
ADM, CCL2 (MCP-1), CCL5 (RANTES), CD69, CD80, CDKN1A (p21CIP1, WAF1), CFB, CXCL10 (INP10), CXCL9 (MIG), IL15, IL1RN, IRF1, MYD88, NCOA3, STAT1, TNFSF10 (TRAIL)
Differentiation & Development
Lymphoid Differentiation & Development​
CD80, CD83, IL12B, IL15, IL2, IL2RA (CD25), IL4, IRF1, STAT5B, TP53 (p53), VCAM1
Myeloid Differentiation & Development​
CCL5 (RANTES), CSF1 (MCSF), CSF2 (GM-CSF), CSF2RB, CSF3 (GCSF), IL4, MMP9, NFKBIA (IκBα, MAD3), STAT5B, TNF
Nervous System Differentiation & Development​
AGT, ALDH3A2, CXCL1 (GRO1, GROa, SCYB1), EGFR (ERBB1), EGR2, IFNG, NR4A2 (NURR1), SNAP25, SOD2, STAT3, TP53 (p53)
Stress Responses
ADM, AKT1, BCL2L1 (BCLXL), BCL2L1 (BCLXL), BCL2L1 (BCLXL), BIRC2 (c-IAP1), CCND1, CDKN1A (p21CIP1, WAF1), GADD45B, IFNG, IL1A, IL1B, MAP2K6 (MEK6, MKK6), NQO1, PDGFB, PLAU (UPA), SOD2, TNF, TP53 (p53), XIAP
NFκB Signaling
Transcription Factors​
NFKB1, NFKB2, NFKBIA (IκBα, MAD3), RELB, STAT1
Regulation of NFκB Signaling​
BIRC2 (c-IAP1), CD40 (TNFRSF5), FASLG (TNFSF6), IL1B, MYD88, REL, RELA, TNF, TNFSF10 (TRAIL)
Transcription Factors
NFκB Signaling​
NFKB1, NFKB2, REL, RELA, RELB
Other Transcription Factors​
EGR2, IRF1, MYC, NR4A2 (NURR1), STAT1, STAT3, STAT5B, TP53 (p53)
Gene Resource List
Array Layout for PCR Plates
File Size: 139.23 KBLanguage: English
Array Layout for Rotor-Gene Q
File Size: 133.61 KBLanguage: English

Resources

Brochures & Guides (3)
Simultaneously profile mRNA, miRNA and lncRNA using a simple, complete workflow
Download Files (3)
For analyzing gene expression data from RT2 Profiler PCR Arrays 
Data analysis file for RT² Profiler PCR Array Housekeeping Genes
Catalog number- 330231
Pathway number- PAXX-000
RNA QC Data Analysis
XLS (484KB)

Data analysis file for RT² ProfilerRT² Profiler™ PCR Array RT2 RNA QC
Catalog number- 330231
Pathway number- PAXX-999

Scientific Posters (1)
Poster for download
Kit Handbooks (1)
For pathway-focused gene expression profiling using real-time RT-PCR
Instrument Technical Documents (2)
For gene expression and genomic analysis
For pathway-focused gene expression analysis
Certificates of Analysis (1)
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