Target List
Stem Cell Specific Markers
Regulation of the Cell Cycle​
APC, AXIN1, CCNA2, CCND1, CCND2, CCNE1, CDK1, CDC42, EP300, FGF1, FGF2 (BFGF), FGF3, FGF4, MYC, NOTCH2, PARD6A, RB1
Chromatin Modification Enzymes & Remodeling Factors​
KAT2A, HDAC2, KAT8, KAT7, RB1, TERT
Symmetric & Asymmetric Cell Division​
DHH, NOTCH1, NOTCH2, NUMB, PARD6A
Self-Renewal Markers​
HSPA9, KAT8, KAT7, NEUROG2, SOX1, SOX2
Cytokines & Growth Factors​
BMP1, BMP2, BMP3, CXCL12 (SDF1), FGF1, FGF2 (BFGF), FGF3, FGF4, GDF2 (BMP9), GDF3 (VGR-2), IGF1, JAG1
Cell-Cell Communication​
DHH, DLL1 (DELTA1), GJA1 (CX43), GJB1 (CX32), GJB2 (CX26), JAG1
Cell Adhesion Molecules​
APC, BGLAP, CD4, CD44, CDH1 (E-Cadherin), CDH2 (N-Cadherin), COL9A1, CTNNA1, CXCL12 (SDF1), NCAM1
Metabolic Markers​
ABCG2 (BCRP), ALDH1A1 (RALDH1), ALDH2, FGFR1
Stem Cell Differentiation Markers
Embryonic Cell Lineage Markers​
ACTC1, ASCL2, FOXA2 (HNF3B), PDX1, ISL1, KRT15, MSX1, MYOD1, TBXT (Brachyury)
Hematopoietic Cell Lineage Markers​
CD3D, CD4, CD8A, CD8B, MME
Mesenchymal Cell Lineage Markers​
ACAN, ALPI, BGLAP, COL1A1, COL2A1, COL9A1, PPARG
Neural Cell Lineage Markers​
CD44, NCAM1, SIGMAR1, S100B, TUBB3
Signaling Pathways Important for Stem Cell Maintenance
Notch Signaling​
DLL1 (DELTA1), DLL3, DTX1, DTX2, DVL1, EP300, KAT2A, HDAC2, JAG1, NOTCH1, NOTCH2, NUMB
WNT Signaling​
ADAR, APC, AXIN1, BTRC (bTrCP), CCND1, FRAT1, FZD1, MYC, PPARD, WNT1