Target List
Dysregulated During Infertility
Cfd, Cldn4, Comp, Crabp2, Dkk1, Esr2 (Erβ), Gadd45a, Gast, Gdf15 (Plab), Gpx3, Igfbp1, Il15, Maoa, Msx1, Olfm1, Sfrp4, Spp1
Receptive Endometrium
Areg, Calca, Csf1 (Mcsf), Egf, Hoxa10, Hoxa11, Lep (Leptin), Lif, Lifr, Muc1 (mucin), Pgr, Ptgs1 (Cox1), Ptgs2 (Cox2), Sell (Lecam-1)
Signal Transduction
Interleukin-1 Signaling​
Il1a, Il1b, Il1r1
WNT Signaling​
Cdh1 (E-cadherin), Ctnnb1, Dkk1, Mmp7, Ptgs2 (Cox2), Sfrp4, Trp53 (p53), Wnt2
Prostaglandin Signaling​
Ptgs1 (Cox1), Ptgs2 (Cox2)
Other Signal Transduction Genes​
Akt1, Egf, Egfr, Gdf15 (Plab), Stat3, Tgfb1
Leukocyte Migration
Calca, Ccl5 (Rantes), Cldn4, Ctnnb1, Cxcl12, Fbn1, Fn1, Icam1, Itga4 (Cd49d), Itgav, Itgb3, Lama1, Lamc2, Mmp2, Mmp7, Mmp9, Sell (Lecam-1), Spp1, Vcam1
Cell Cycle
Ccnb1, Gadd45a, Mki67, Pcna, Stmn1, Tgfb1, Trp53 (p53)
Coagulation
C2, C3, Cd55, Cfd, F3
Apoptosis
Bax, Bcl2, Casp3, Comp, Gadd45a, Il1b, Msx1, Tnf, Tnfrsf10b (Dr5), Trp53 (p53)
Cytokines
Ccl5 (Rantes), Csf1 (Mcsf), Cxcl12, Il11, Il15, Il1a, Il1b, Il1r1, Il6, Lifr, Tgfb1
Other Genes Involved in Pregnancy
Anxa2, Apod, Ar, Esr1 (Erα), Hbegf, Igf1, Kdr (Vegfr2), Mid1, Pgf, Prl, Sod1, Timp1, Vegfa