Kank4 Gene Summary [Mouse]
Predicted to be involved in negative regulation of actin filament polymerization. Predicted to act upstream of or within negative regulation of stress fiber assembly. Predicted to be located in cytosol and microtubule cytoskeleton. Predicted to be active in cytoplasm and cytoskeleton. Is expressed in extrinsic ocular muscle; lung; metanephros; and ureteric tip. Orthologous to human KANK4 (KN motif and ankyrin repeat domains 4). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Kank4 |
| Official Name | KN motif and ankyrin repeat domains 4 [Source:MGI Symbol;Acc:MGI:3043381] |
| Ensembl ID | ENSMUSG00000035407 |
| Bio databases IDs | |
| Aliases | KN motif and ankyrin repeat domains 4 |
| Synonyms | ANKRD38, BC060737, C130031J23, dJ1078M7.1, KN motif and ankyrin repeat domains 4, LOC163782 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Kank4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ankyrin repeats (many copies)
- KN motif
- Ankyrin repeats (3 copies)
- protein binding
- Ankyrin repeat
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Kank4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of actin filament polymerization
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
- cytoskeleton
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding