KANK4 Gene Summary [Human]
Predicted to be involved in negative regulation of actin filament polymerization. Located in cytosol and microtubule cytoskeleton. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | KANK4 |
| Official Name | KN motif and ankyrin repeat domains 4 [Source:HGNC Symbol;Acc:HGNC:27263] |
| Ensembl ID | ENSG00000132854 |
| Bio databases IDs | |
| Aliases | KN motif and ankyrin repeat domains 4 |
| Synonyms | ANKRD38, BC060737, C130031J23, dJ1078M7.1, KN motif and ankyrin repeat domains 4, LOC163782 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human KANK4 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Ankyrin repeats (many copies)
- KN motif
- Ankyrin repeats (3 copies)
- protein binding
- Ankyrin repeat
- ankyrin repeats
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microtubule cytoskeleton
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human KANK4 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- negative regulation of actin filament polymerization
Cellular Component
Where in the cell the gene product is active
- microtubule cytoskeleton
- cytoskeleton
- cytoplasm
- cytosol
Molecular Function
What the gene product does at the molecular level
- protein binding