Ifi27l2a Gene Summary [Mouse]

Predicted to enable identical protein binding activity and molecular adaptor activity. Acts upstream of or within response to virus. Predicted to be located in nuclear envelope. Predicted to be active in mitochondrial membrane. Is expressed in embryo. Orthologous to several human genes including IFI27L2 (interferon alpha inducible protein 27 like 2). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ifi27l2a
Official Name
interferon, alpha-inducible protein 27 like 2A [Source:MGI Symbol;Acc:MGI:1924183]
Ensembl ID
ENSMUSG00000079017
Bio databases IDs NCBI: 76933 Ensembl: ENSMUSG00000079017
Aliases interferon, alpha-inducible protein 27 like 2A
Synonyms 2310061N23Rik, FAM14A, Ifi27, Ifi27l2a, interferon alpha inducible protein 27 like 2, interferon, alpha-inducible protein 27 like 2A, interferon α inducible protein 27 like 2, interferon, α-inducible protein 27 like 2A, Isg12, ISG12B, Isg12(b1), TLH29
Species
Mouse, Mus musculus
OrthologiesHuman

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ifi27l2a often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Interferon-induced 6-16 family
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • squamous-cell carcinoma
  • insulin-dependent diabetes mellitus
  • squamous cell cancer
regulated by
role in cell
  • apoptosis
  • formation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial membrane
  • nuclear envelope

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Ifi27l2a gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • apoptotic process
  • apoptotic signaling pathway

Cellular Component

Where in the cell the gene product is active
  • mitochondrial membrane
  • mitochondrion

Gene-Specific Assays for Results You Can Trust

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