IFI27L2 Gene Summary [Human]

Involved in apoptotic process. Located in mitochondrial membrane. [provided by Alliance of Genome Resources, Apr 2022]

Details

Type
Retained Intron
Official Symbol
IFI27L2
Official Name
interferon alpha inducible protein 27 like 2 [Source:HGNC Symbol;Acc:HGNC:19753]
Ensembl ID
ENSG00000119632
Bio databases IDs NCBI: 83982 Ensembl: ENSG00000119632
Aliases interferon alpha inducible protein 27 like 2
Synonyms 2310061N23Rik, FAM14A, Ifi27, Ifi27l2a, interferon alpha inducible protein 27 like 2, interferon, alpha-inducible protein 27 like 2A, interferon α inducible protein 27 like 2, interferon, α-inducible protein 27 like 2A, Isg12, ISG12B, Isg12(b1), TLH29
Species
Human, Homo sapiens
OrthologiesMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human IFI27L2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Interferon-induced 6-16 family
  • identical protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • squamous-cell carcinoma
  • insulin-dependent diabetes mellitus
  • squamous cell cancer
regulated by
role in cell
  • apoptosis
  • formation

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Mitochondria
  • mitochondrial membrane
  • nuclear envelope

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the human IFI27L2 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • apoptotic process
  • apoptotic signaling pathway

Cellular Component

Where in the cell the gene product is active
  • mitochondrial membrane
  • mitochondrion

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.