Ugt1a6 Gene Summary [Rat]
Predicted to enable enzyme binding activity; glucuronosyltransferase activity; and protein dimerization activity. Involved in cellular response to ethanol; cellular response to glucocorticoid stimulus; and liver development. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Orthologous to human UGT1A4 (UDP glucuronosyltransferase family 1 member A4) and UGT1A5 (UDP glucuronosyltransferase family 1 member A5). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Ugt1a6 |
| Official Name | UDP glucuronosyltransferase family 1 member A6 [Source:RGD Symbol;Acc:620949] |
| Ensembl ID | ENSRNOG00000018740 |
| Bio databases IDs | |
| Aliases | UDP glucuronosyltransferase family 1 member A6 |
| Synonyms | A10', A13, UDP glucuronosyltransferase 1 family, polypeptide A7C, UDPGT 1-7, Ugt1, Ugt1a10, UGT1A7, Ugt1a8 |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Ugt1a6 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- glycosyltransferase family 1 and related proteins with GTB topology
- fatty acid binding
- enzyme inhibitor activity
- protein kinase C binding
- enzyme binding
- enzyme
- retinoid binding
- UDP-glucoronosyl and UDP-glucosyl transferase
- identical protein binding
- glucuronosyltransferase
- steroid binding
- binding protein
- protein homodimerization
- protein heterodimerization
Pathways
Biological processes and signaling networks where the Ugt1a6 gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Endoplasmic Reticulum
- microsome