Ugt1a7c Gene Summary [Mouse]

Predicted to enable several functions, including monocarboxylic acid binding activity; protein dimerization activity; and protein kinase C binding activity. Predicted to be involved in coumarin catabolic process; estrogen catabolic process; and liver development. Predicted to be located in endoplasmic reticulum membrane. Predicted to be active in endoplasmic reticulum. Is expressed in nervous system; stomach; and urinary system. Human ortholog(s) of this gene implicated in alcoholic pancreatitis and pancreatic cancer. Orthologous to several human genes including UGT1A10 (UDP glucuronosyltransferase family 1 member A10); UGT1A7 (UDP glucuronosyltransferase family 1 member A7); and UGT1A8 (UDP glucuronosyltransferase family 1 member A8). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Ugt1a7c
Official Name
UDP glucuronosyltransferase 1 family, polypeptide A7C [Source:MGI Symbol;Acc:MGI:3032636]
Ensembl ID
ENSMUSG00000090124
Bio databases IDs NCBI: 394432 Ensembl: ENSMUSG00000090124
Aliases UDP glucuronosyltransferase 1 family, polypeptide A7C
Synonyms A10', A13, UDP glucuronosyltransferase 1 family, polypeptide A7C, UDPGT 1-7, Ugt1, Ugt1a10, UGT1A7, Ugt1a8
Species
Mouse, Mus musculus
OrthologiesRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Ugt1a7c often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • glycosyltransferase family 1 and related proteins with GTB topology
  • fatty acid binding
  • enzyme inhibitor activity
  • protein kinase C binding
  • enzyme binding
  • enzyme
  • retinoid binding
  • UDP-glucoronosyl and UDP-glucosyl transferase
  • identical protein binding
  • glucuronosyltransferase
  • steroid binding
  • binding protein
  • protein homodimerization
  • protein heterodimerization

Pathways

Biological processes and signaling networks where the Ugt1a7c gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulates
  • coumarin
  • estrogen
  • levothyroxine
  • Ugt1a7c

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • Endoplasmic Reticulum
  • microsome

Gene-Specific Assays for Results You Can Trust

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