Acadsb Gene Summary [Rat]
Enables electron transfer activity and short-chain fatty acyl-CoA dehydrogenase activity. Acts upstream of or within acyl-CoA metabolic process. Predicted to be located in membrane and mitochondrial matrix. Predicted to be active in mitochondrion. Orthologous to human ACADSB (acyl-CoA dehydrogenase short/branched chain). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Acadsb |
| Official Name | acyl-CoA dehydrogenase, short/branched chain [Source:RGD Symbol;Acc:2013] |
| Ensembl ID | ENSRNOG00000020624 |
| Bio databases IDs | |
| Aliases | acyl-CoA dehydrogenase, short/branched chain |
| Synonyms | 1300003O09Rik, 2-MEBCAD, ACAD7, Acyl-coa dehydrogenase, acyl-CoA dehydrogenase short/branched chain, acyl-CoA dehydrogenase, short/branched chain, acyl-Coenzyme A dehydrogenase, short/branched chain, BB066609, LOC100912409, LOC103691247, SBCAD |
| Species | Rat, Rattus norvegicus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Acadsb often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- electron carrier
- short branched-chain acyl-CoA dehydrogenase
- Acyl-CoA dehydrogenase, C-terminal domain
- acyl-CoA dehydrogenase
- Acyl-CoA dehydrogenase, middle domain
- enzyme
- 2-methylacyl-CoA dehydrogenase
- identical protein binding
- Acyl-CoA dehydrogenase, N-terminal domain
Pathways
Biological processes and signaling networks where the Acadsb gene in rat plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
- liver cancer
- epithelial cancer
- non-insulin-dependent diabetes mellitus
- hepatocellular carcinoma
- short/branched-chain acyl-CoA dehydrogenase deficiency
- hereditary disorder
- nonalcoholic steatohepatitis
- polycystic kidney disease
- renal clear cell adenocarcinoma
- renal clear cell cancer
regulates
- FAS
- propionylcarnitine
- fatty acid
- acyl-coenzyme A
- isoleucine
role in cell
- alternative splicing in
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial matrix
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the rat Acadsb gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- isoleucine catabolic process
- fatty acid metabolic process
Cellular Component
Where in the cell the gene product is active
- mitochondrial matrix
- mitochondrion
Molecular Function
What the gene product does at the molecular level
- acyl-CoA dehydrogenase activity
- 2-methylacyl-CoA dehydrogenase activity
- identical protein binding
- flavin adenine dinucleotide binding
- butyryl-CoA dehydrogenase activity
- short-branched-chain-acyl-CoA dehydrogenase activity