ACSBG2 Gene Summary [Human]
Enables acyl-CoA hydrolase activity and arachidonate-CoA ligase activity. Acts upstream of or within fatty acid metabolic process. Located in cytosol and mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | ACSBG2 |
| Official Name | acyl-CoA synthetase bubblegum family member 2 [Source:HGNC Symbol;Acc:HGNC:24174] |
| Ensembl ID | ENSG00000130377 |
| Bio databases IDs | |
| Aliases | acyl-CoA synthetase bubblegum family member 2, bubblegum related protein |
| Synonyms | acyl-CoA synthetase bubblegum family member 2, BGR, BRGL, PRTD-NY3 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human ACSBG2 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- long-chain-fatty-acid-CoA ligase
- fatty-acid ligase
- arachidonate-CoA ligase
- AMP-binding enzyme
- CoA-ligase
- acyl-CoA ligase (AMP-forming), exosortase A-associated
- Adenylate forming domain, Class I superfamily
- enzyme
- acyl-CoA hydrolase
- amino acid adenylation domain
Pathways
Biological processes and signaling networks where the ACSBG2 gene in human plays a role, providing insight into its function and relevance in health or disease.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- microsomal fraction
- Mitochondria
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human ACSBG2 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- long-chain fatty acid biosynthetic process
- spermatogenesis
- long-chain fatty-acyl-CoA biosynthetic process
- cell differentiation
- fatty acid metabolic process
Cellular Component
Where in the cell the gene product is active
- cytoplasm
- mitochondrion
- membrane
- cytosol
Molecular Function
What the gene product does at the molecular level
- ATP binding
- very long-chain fatty acid-CoA ligase activity
- arachidonate-CoA ligase activity
- acyl-CoA hydrolase activity
- long-chain fatty acid-CoA ligase activity