Rpe Gene Summary [Mouse]
Enables D-ribulose-phosphate 3-epimerase activity. Involved in pentose-phosphate shunt. Is active in cytosol. Is expressed in several structures, including alimentary system; central nervous system; genitourinary system; integumental system; and nose. Orthologous to several human genes including RPE (ribulose-5-phosphate-3-epimerase). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Nonsense Mediated Decay |
| Official Symbol | Rpe |
| Official Name | ribulose-5-phosphate-3-epimerase [Source:MGI Symbol;Acc:MGI:1913896] |
| Ensembl ID | ENSMUSG00000026005 |
| Bio databases IDs | |
| Aliases | ribulose-5-phosphate-3-epimerase |
| Synonyms | 2810429B02RIK, 5730518J08Rik, ribulose-5-phosphate-3-epimerase, RPE2-1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Rpe often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribulose-phosphate 3-epimerase
- monosaccharide binding
- TIM-like beta/alpha barrel domains
- metal ion binding
- protein homodimerization
- enzyme
- protein binding
- carbohydrate binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Rpe gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- pentose-phosphate shunt, non-oxidative branch
- carbohydrate metabolic process
- pentose-phosphate shunt
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- protein homodimerization activity
- metal ion binding
- ribulose-phosphate 3-epimerase activity