RPE Gene Summary [Human]
Enables metal ion binding activity; protein homodimerization activity; and ribulose-phosphate 3-epimerase activity. Involved in carbohydrate metabolic process and pentose-phosphate shunt. Located in extracellular exosome. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | RPE |
| Official Name | ribulose-5-phosphate-3-epimerase [Source:HGNC Symbol;Acc:HGNC:10293] |
| Ensembl ID | ENSG00000197713 |
| Bio databases IDs | |
| Aliases | ribulose-5-phosphate-3-epimerase |
| Synonyms | 2810429B02RIK, 5730518J08Rik, ribulose-5-phosphate-3-epimerase, RPE2-1 |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human RPE often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- ribulose-phosphate 3-epimerase
- monosaccharide binding
- TIM-like beta/alpha barrel domains
- metal ion binding
- protein homodimerization
- enzyme
- protein binding
- carbohydrate binding
- identical protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- cytosol
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human RPE gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- pentose-phosphate shunt, non-oxidative branch
- carbohydrate metabolic process
- pentose-phosphate shunt
Cellular Component
Where in the cell the gene product is active
- extracellular vesicular exosome
- cytosol
Molecular Function
What the gene product does at the molecular level
- identical protein binding
- protein binding
- protein homodimerization activity
- metal ion binding
- ribulose-phosphate 3-epimerase activity