Txnl4b Gene Summary [Mouse]
Predicted to act upstream of or within mRNA splicing, via spliceosome and positive regulation of cell population proliferation. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of U4/U6 x U5 tri-snRNP complex; U5 snRNP; and spliceosomal complex. Orthologous to human TXNL4B (thioredoxin like 4B). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Txnl4b |
| Official Name | thioredoxin-like 4B [Source:MGI Symbol;Acc:MGI:2443724] |
| Ensembl ID | ENSMUSG00000031723 |
| Bio databases IDs | |
| Aliases | thioredoxin-like 4B |
| Synonyms | AI595343, D530025J19Rik, Dim2, DLP, RGD1305127, thioredoxin-like 4B |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Txnl4b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
- Mitosis protein DIM1
- enzyme
- protein binding
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- cytosol
- nucleoplasm
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Txnl4b gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- nuclear mRNA splicing, via spliceosome
Cellular Component
Where in the cell the gene product is active
- U4/U6 x U5 tri-snRNP complex
- U5 snRNP
- cytosol
- spliceosomal complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding