Txnl4b Gene Summary [Rat]

Predicted to be involved in mRNA splicing, via spliceosome. Predicted to be located in cytosol and nucleoplasm. Predicted to be part of U4/U6 x U5 tri-snRNP complex; U5 snRNP; and spliceosomal complex. Orthologous to human TXNL4B (thioredoxin like 4B). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Txnl4b
Official Name
thioredoxin-like 4B [Source:RGD Symbol;Acc:1305127]
Ensembl ID
ENSRNOG00000021379
Bio databases IDs NCBI: 292008 Ensembl: ENSRNOG00000021379
Aliases thioredoxin-like 4B
Synonyms AI595343, D530025J19Rik, Dim2, DLP, RGD1305127, thioredoxin-like 4B
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Txnl4b often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • Protein Disulfide Oxidoreductases and Other Proteins with a Thioredoxin fold
  • Mitosis protein DIM1
  • enzyme
  • protein binding

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
regulated by
regulates
  • Adml
role in cell
  • proliferation
  • G2/M phase
  • splicing by
  • S phase
  • necroptosis
  • DNA damage repair in
  • radiosensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Nucleus
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Txnl4b gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • nuclear mRNA splicing, via spliceosome

Cellular Component

Where in the cell the gene product is active
  • U4/U6 x U5 tri-snRNP complex
  • U5 snRNP
  • cytosol
  • spliceosomal complex
  • nucleoplasm

Molecular Function

What the gene product does at the molecular level
  • protein binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.