Utf1 Gene Summary [Mouse]
Enables HMG box domain binding activity; TBP-class protein binding activity; and transcription coactivator activity. Involved in positive regulation of transcription by RNA polymerase II. Located in nucleus. Is expressed in several structures, including early conceptus; embryo ectoderm; gonad; and limb mesenchyme. Orthologous to human UTF1 (undifferentiated embryonic cell transcription factor 1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Utf1 |
| Official Name | undifferentiated embryonic cell transcription factor 1 [Source:MGI Symbol;Acc:MGI:1276125] |
| Ensembl ID | ENSMUSG00000047751 |
| Bio databases IDs | |
| Aliases | undifferentiated embryonic cell transcription factor 1 |
| Synonyms | undifferentiated embryonic cell transcription factor 1 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Utf1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- transcription regulator
- transcription co-activator
- protein domain specific binding
- protein binding
- TATA-binding protein binding
Pathways
Biological processes and signaling networks where the Utf1 gene in mouse plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Utf1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- male gonad development
- positive regulation of transcription from RNA polymerase II promoter
- regulation of transcription from RNA polymerase II promoter
Cellular Component
Where in the cell the gene product is active
- nucleus
Molecular Function
What the gene product does at the molecular level
- protein binding
- transcription coactivator activity