Trip10 Gene Summary [Mouse]

Predicted to enable identical protein binding activity. Predicted to be involved in epithelial to mesenchymal transition; negative regulation of cardiac muscle cell apoptotic process; and positive regulation of cell growth involved in cardiac muscle cell development. Predicted to be located in nucleoplasm. Is expressed in several structures, including clavicle; cranium; inner ear; submandibular gland primordium; and trigeminal ganglion. Orthologous to human TRIP10 (thyroid hormone receptor interactor 10). [provided by Alliance of Genome Resources, Jul 2025]

Details

Type
Protein Coding
Official Symbol
Trip10
Official Name
thyroid hormone receptor interactor 10 [Source:MGI Symbol;Acc:MGI:2146901]
Ensembl ID
ENSMUSG00000019487
Bio databases IDs NCBI: 106628 Ensembl: ENSMUSG00000019487
Aliases thyroid hormone receptor interactor 10
Synonyms CIP4, Cip4/2, HSTP, STOT, STP, thyroid hormone receptor interactor 10
Species
Mouse, Mus musculus
OrthologiesHumanRat

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Trip10 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • GTPase binding domain
  • microtubule binding domain
  • Fes/CIP4, and EFC/F-BAR homology domain
  • protein binding
  • Bin/Amphiphysin/Rvs domain
  • identical protein binding
  • HR1
  • Src Homology 3 domain superfamily

Pathways

Biological processes and signaling networks where the Trip10 gene in mouse plays a role, providing insight into its function and relevance in health or disease.

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
disease
  • delayed hypersensitive reaction
regulated by
regulates
role in cell
  • cell death
  • migration
  • activation in
  • activity
  • function
  • polarization
  • invasion
  • assembly
  • formation
  • crizotinib sensitivity

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Cytoplasm
  • soluble fraction
  • intracellular membrane-bounded organelle
  • cell periphery
  • cellular membrane
  • Nucleus
  • microtubules
  • cytosol
  • nucleoplasm

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the mouse Trip10 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • cell communication
  • signal transduction
  • endocytosis
  • actin cytoskeleton organization

Cellular Component

Where in the cell the gene product is active
  • Golgi apparatus
  • cell projection
  • phagocytic cup
  • lysosome
  • nucleoplasm
  • extracellular vesicular exosome
  • cytoskeleton
  • perinuclear region of cytoplasm
  • cytoplasm
  • cell cortex
  • intracellular membrane-bounded organelle
  • cytosol

Molecular Function

What the gene product does at the molecular level
  • identical protein binding
  • protein binding
  • lipid binding

Gene-Specific Assays for Results You Can Trust

Streamline your workflow with assays designed for this gene. Our targeted dPCR and qPCR assays help you generate meaningful data – efficiently and accurately.