Gng8 Gene Summary [Mouse]
Predicted to enable G-protein beta-subunit binding activity. Acts upstream of or within cellular response to pheromone; nose development; and social behavior. Predicted to be part of heterotrimeric G-protein complex. Is expressed in cochlear duct epithelium; retina; and spleen. Orthologous to human GNG8 (G protein subunit gamma 8). [provided by Alliance of Genome Resources, Apr 2025]
Details
| Type | Protein Coding |
| Official Symbol | Gng8 |
| Official Name | guanine nucleotide binding protein (G protein), gamma 8 [Source:MGI Symbol;Acc:MGI:109163] |
| Ensembl ID | ENSMUSG00000063594 |
| Bio databases IDs | |
| Aliases | guanine nucleotide binding protein (G protein), gamma 8 |
| Synonyms | G gamma 8C, G protein subunit gamma 8, G protein subunit γ 8, G protein γ 8, GTP-binding protein gamma subunit, GTP-binding protein γ subunit, guanine nucleotide binding protein (G protein), gamma 8, guanine nucleotide binding protein (G protein), γ 8, G(y)8, G γ 8C, HG3E |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Gng8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GGL
- protein binding
- GGL domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Gng8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- social behavior
- G-protein coupled receptor signaling pathway
- nose development
- cellular response to pheromone
Cellular Component
Where in the cell the gene product is active
- heterotrimeric G-protein complex
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- G-protein beta-subunit binding
- GTPase activity