GNG8 Gene Summary [Human]
Predicted to enable G-protein beta-subunit binding activity. Predicted to be involved in G protein-coupled receptor signaling pathway. Predicted to act upstream of or within cellular response to pheromone; nose development; and social behavior. Predicted to be located in plasma membrane. Predicted to be part of heterotrimeric G-protein complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Protein Coding |
| Official Symbol | GNG8 |
| Official Name | G protein subunit gamma 8 [Source:HGNC Symbol;Acc:HGNC:19664] |
| Ensembl ID | ENSG00000167414 |
| Bio databases IDs | |
| Aliases | G protein subunit gamma 8 |
| Synonyms | G gamma 8C, G protein subunit gamma 8, G protein subunit γ 8, G protein γ 8, GTP-binding protein gamma subunit, GTP-binding protein γ subunit, guanine nucleotide binding protein (G protein), gamma 8, guanine nucleotide binding protein (G protein), γ 8, G(y)8, G γ 8C, HG3E |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human GNG8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- GGL
- protein binding
- GGL domain
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human GNG8 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- social behavior
- G-protein coupled receptor signaling pathway
- nose development
- cellular response to pheromone
Cellular Component
Where in the cell the gene product is active
- heterotrimeric G-protein complex
- plasma membrane
Molecular Function
What the gene product does at the molecular level
- protein binding
- G-protein beta-subunit binding
- GTPase activity