Gng8 Gene Summary [Rat]

Predicted to enable G-protein beta-subunit binding activity. Involved in nervous system development. Predicted to be part of heterotrimeric G-protein complex. Orthologous to human GNG8 (G protein subunit gamma 8). [provided by Alliance of Genome Resources, Apr 2025]

Details

Type
Protein Coding
Official Symbol
Gng8
Official Name
G protein subunit gamma 8 [Source:RGD Symbol;Acc:620808]
Ensembl ID
ENSRNOG00000016701
Bio databases IDs NCBI: 245986 Ensembl: ENSRNOG00000016701
Aliases G protein subunit gamma 8
Synonyms G gamma 8C, G protein subunit gamma 8, G protein subunit γ 8, G protein γ 8, GTP-binding protein gamma subunit, GTP-binding protein γ subunit, guanine nucleotide binding protein (G protein), gamma 8, guanine nucleotide binding protein (G protein), γ 8, G(y)8, G γ 8C, HG3E
Species
Rat, Rattus norvegicus
OrthologiesHumanMouse

Protein Domains

A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in rat Gng8 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
  • GGL
  • protein binding
  • GGL domain

Top Findings

The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
binds
disease
  • Crohn disease
  • preeclampsia
regulated by

Subcellular Expression

Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
  • Plasma Membrane

Gene Ontology Annotations

Describes the biological processes, cellular components, and molecular functions associated with the rat Gng8 gene, providing context for its role in the cell.

Biological Process

Functions and activities the gene product is involved in
  • social behavior
  • G-protein coupled receptor signaling pathway
  • nose development
  • cellular response to pheromone

Cellular Component

Where in the cell the gene product is active
  • heterotrimeric G-protein complex
  • plasma membrane

Molecular Function

What the gene product does at the molecular level
  • protein binding
  • G-protein beta-subunit binding
  • GTPase activity

Gene-Specific Assays for Results You Can Trust

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