Brix1 Gene Summary [Mouse]
Predicted to enable RNA binding activity. Predicted to be involved in ribosomal large subunit assembly. Predicted to be located in chromosome. Predicted to be active in nucleolus. Orthologous to human BRIX1 (biogenesis of ribosomes BRX1). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Brix1 |
| Official Name | BRX1, biogenesis of ribosomes [Source:MGI Symbol;Acc:MGI:1915082] |
| Ensembl ID | ENSMUSG00000022247 |
| Bio databases IDs | |
| Aliases | BRX1, biogenesis of ribosomes |
| Synonyms | 1110064N10Rik, biogenesis of ribosomes BRX1, BRIX, BRX1, biogenesis of ribosomes, BXDC2, RGD1308508 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Brix1 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- Brix domain
- protein binding
- The Brix domain is found in a number of eukaryotic proteins
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Nucleus
- chromosome
- nucleoli
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the mouse Brix1 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- rRNA processing
- ribosomal large subunit assembly
Cellular Component
Where in the cell the gene product is active
- chromosome
- nucleolus
Molecular Function
What the gene product does at the molecular level
- RNA binding
- protein binding
- rRNA binding