Cd177 Gene Summary [Mouse]
Predicted to enable calcium-dependent protein binding activity; integrin binding activity; and protease binding activity. Predicted to be involved in several processes, including neutrophil extravasation; positive regulation of superoxide anion generation; and regulation of vesicle-mediated transport. Predicted to be located in plasma membrane and tertiary granule membrane. Predicted to be active in plasma membrane raft. Is expressed in bone marrow; liver; spleen; and thymus. Orthologous to human CD177 (CD177 molecule). [provided by Alliance of Genome Resources, Jul 2025]
Details
| Type | Protein Coding |
| Official Symbol | Cd177 |
| Official Name | CD177 antigen [Source:MGI Symbol;Acc:MGI:1916141] |
| Ensembl ID | ENSMUSG00000052212 |
| Bio databases IDs | |
| Aliases | CD177 antigen |
| Synonyms | 1190003K14Rik, CD177 antigen, CD177 molecule, LOC100909700, Pdp3, RGD1562941 |
| Species | Mouse, Mus musculus |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in mouse Cd177 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- calcium-dependent protein binding
- TFP_LU_ECD_LYPD4_rpt2_like
- protease binding
- integrin binding
- TFP
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Plasma Membrane
- secretory granule membrane
- tertiary granule membrane
- membrane rafts