DNAJC11 Gene Summary [Human]
Involved in cristae formation. Located in mitochondrial outer membrane and nuclear speck. Part of MIB complex. Colocalizes with MICOS complex and SAM complex. [provided by Alliance of Genome Resources, Apr 2022]
Details
| Type | Processed Transcript |
| Official Symbol | DNAJC11 |
| Official Name | DnaJ heat shock protein family (Hsp40) member C11 [Source:HGNC Symbol;Acc:HGNC:25570] |
| Ensembl ID | ENSG00000007923 |
| Bio databases IDs | |
| Aliases | DnaJ heat shock protein family (Hsp40) member C11 |
| Synonyms | dJ126A5.1, DnaJ heat shock protein family (Hsp40) member C11, E030019A03Rik |
| Species | Human, Homo sapiens |
| Orthologies |
Protein Domains
A protein domain is a distinct structural or functional region within a protein that can evolve, function, and exist independently of the rest of the protein chain. These domains in human DNAJC11 often fold into stable, three-dimensional structures and are associated with specific biological functions, such as binding to DNA, other proteins, or small molecules.
- DnaJ-like protein C11, C-terminal
- DnaJ domain
- DnaJ
- DnaJ molecular chaperone homology domain
- protein binding
Pathways
Biological processes and signaling networks where the DNAJC11 gene in human plays a role, providing insight into its function and relevance in health or disease.
Top Findings
The most significant associations for this gene, including commonly observed domains, pathway involvement, and functional highlights based on current data.
Subcellular Expression
Locations within the cell where the protein is known or predicted to be active, providing insight into its function and cellular context.
- Cytoplasm
- Mitochondria
- mitochondrial outer membrane
- nucleoplasm
- nuclear speckles
Gene Ontology Annotations
Describes the biological processes, cellular components, and molecular functions associated with the human DNAJC11 gene, providing context for its role in the cell.
Biological Process
Functions and activities the gene product is involved in
- cristae formation
- inner mitochondrial membrane organization
Cellular Component
Where in the cell the gene product is active
- nuclear speck
- mitochondrion
- mitochondrial sorting and assembly machinery complex
- nucleoplasm
Molecular Function
What the gene product does at the molecular level
- protein binding